10 kda 4-arm peg thiol Search Results


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Laysan Bio 4-arm thiolated peg (peg4sh
Hydrogel formulations and stress-relaxation time. All polymers are in wt%. EL: Elastic, VE: Viscoelastic.
4 Arm Thiolated Peg (Peg4sh, supplied by Laysan Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Hydrogel formulations and stress-relaxation time. All polymers are in wt%. EL: Elastic, VE: Viscoelastic.

Journal: Materials Today Bio

Article Title: Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions

doi: 10.1016/j.mtbio.2023.100576

Figure Lengend Snippet: Hydrogel formulations and stress-relaxation time. All polymers are in wt%. EL: Elastic, VE: Viscoelastic.

Article Snippet: 2-(2-Carboxyethylsulfanylthiocarbonylsulfanyl)propionic acid (CPA, 95%, Sigma-Aldrich), methanol (ACS reagent, 99.8%, Sigma-Aldrich), N,N′-diisopropylcarbodiimide (DIC, Chem-Impex), 3,4-dihydroxyphenylacetic acid (DOPAC, Ambeed), 4-dimethylaminopyridine (DMAP, Aldrich), dimethylformamide (DMF, anhydrous, Alfa Aesar), lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, ≥95%, Sigma-Aldrich), 4-arm thiolated PEG (PEG4SH, 10 ​kDa, Laysan Bio), pyridine (Fisher) were used as received.

Techniques:

Stress-relaxation of thiol-norbornene RAFT polymer hydrogels. (A) Effect of polymer compositions on stress-relaxation. (B) Effect of PHD content on stress-relaxation. (C, D) Tuning hydrogel compositions for matching shear moduli (C) with varying tan(δ) (D). Elastic gels: 3 ​wt% PEH NB , 2 ​wt% PHD, 0.5 ​wt% PEG4SH, 3 ​wt% GelSH. Viscoelastic gels: 3 ​wt% PEH NB A, 2 ​wt% PHD, and 3 ​wt% GelSH. Additional PEG4SH (0.5 ​wt%) was included in the elastic hydrogel group to ensure the two sets of gels displayed similar G’. (E, F) Effect of collagenase-mediated gel degradation of G′ and stress-relaxation (G’/G′ 0 ) curves for elastic (E) and viscoelastic hydrogels (F). Detailed hydrogel formulations for A, B, E, F are listed in <xref ref-type=Table 3 . " width="100%" height="100%">

Journal: Materials Today Bio

Article Title: Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions

doi: 10.1016/j.mtbio.2023.100576

Figure Lengend Snippet: Stress-relaxation of thiol-norbornene RAFT polymer hydrogels. (A) Effect of polymer compositions on stress-relaxation. (B) Effect of PHD content on stress-relaxation. (C, D) Tuning hydrogel compositions for matching shear moduli (C) with varying tan(δ) (D). Elastic gels: 3 ​wt% PEH NB , 2 ​wt% PHD, 0.5 ​wt% PEG4SH, 3 ​wt% GelSH. Viscoelastic gels: 3 ​wt% PEH NB A, 2 ​wt% PHD, and 3 ​wt% GelSH. Additional PEG4SH (0.5 ​wt%) was included in the elastic hydrogel group to ensure the two sets of gels displayed similar G’. (E, F) Effect of collagenase-mediated gel degradation of G′ and stress-relaxation (G’/G′ 0 ) curves for elastic (E) and viscoelastic hydrogels (F). Detailed hydrogel formulations for A, B, E, F are listed in Table 3 .

Article Snippet: 2-(2-Carboxyethylsulfanylthiocarbonylsulfanyl)propionic acid (CPA, 95%, Sigma-Aldrich), methanol (ACS reagent, 99.8%, Sigma-Aldrich), N,N′-diisopropylcarbodiimide (DIC, Chem-Impex), 3,4-dihydroxyphenylacetic acid (DOPAC, Ambeed), 4-dimethylaminopyridine (DMAP, Aldrich), dimethylformamide (DMF, anhydrous, Alfa Aesar), lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, ≥95%, Sigma-Aldrich), 4-arm thiolated PEG (PEG4SH, 10 ​kDa, Laysan Bio), pyridine (Fisher) were used as received.

Techniques: